Digsby helps you manage all your IM, e-mail, and social network accounts from one easy-to-use application. Digsby lets you chat with all your friends on AIM, MSN, Yahoo, ICQ, Google Talk, Facebook Chat, and Jabber with one simple to manage buddy list. It provides notifications when new e-mails arrive and lets you perform actions such as “Mark as Read” or “Report Spam” without having to go to your inbox while also keeping you up-to-date on what’s happening on your social networks with pop-up notifications and a news feed of recent events for Facebook, MySpace, and Twitter.

FireStatus is a Firefox 3 extension that allows you to send status updates, notes and URL links simultaneously to multiple social networks and services, like Twitter, FaceBook and FriendFeed. It also displays updates from these services in notification popups, for a more “live” communication with your friends.
Note
Firefox 3.0 – 3.1b2

Twitbin is a firefox extension that allows you to keep up with all of your Twitter conversations right from your browser sidebar. Send messages, receive messages, share links, and more from Twitbin, the best twitter addon for firefox out there.
Note
Firefox 1.5 – 3.1b2

Core Protection for Your PC. 10 years of malware experience combined in one dynamic application. Ad-Aware – Anniversary Edition offers radically improved performance and efficiency, along with comprehensive malware protection. With real-time monitoring, threat alerts, and automatic updates you can rest easy knowing that you are protected.

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Twitter Gadget by Google. What are you doing? Read and update Twitters right on your desktop! Google Desktop 1.0 or higher required. Twitter account required.